The Entourage Effect
When preparing a tincture or whole plant medicinal extract many solvents will take up cannabis resin, meaning a mix of cannabinoids and terpenes. A complete medicinal extract is a three part synergy of cannabinoids, terpenoids and flavonoids, which is the third component of cannabis synergism of the entourage effect.
The flavonoids, often called bioflavonoids are represented in cannabis by common vegetable compounds such as, Quercetin and Rutin, all with well documented medicinal beneficial effects along with many others including Cannflavin A and B. Of most importance is the extraction of the flavonoid fraction for a Whole Plant Extract.
The importance of the synergy of the three significant therapeutic classes of compounds is called The Entourage Effect. Whole plant extractions for medical use should take up all three families of medicine with great efficiency and minimise the amount of chlorophyll’s, concrete oils and waxes that have little or no therapeutic value.
Ethanol is a solvent that will take up all three medicinal fractions but when used in a typical extraction has some drawbacks. The problem with ethanol is it's too non-selective. It takes up chlorophyll and other undesirable fractions that make it's oils and tinctures "green" and bitter.
The answer lies in changing the traits of ethanol and making it very selective for a whole plant extraction, and very non-selective for the other non-desirables. This is done by freezer cooling ethanol and the raw cannabis material to extract, then doing a three minute wash and freezing cold rinse. This is called the Quick Cold Wash. The result is a near clear extract or tincture that can be easily made in minutes.
Ethanol is a relatively safe solvent, whose characteristics can be manipulated with temperature, to be highly selective for medicinal compounds, while leaving undesirable waxes, chlorophyll and concrete oils behind. Ethanol is a powerful stripper of the cannabinoids, terpenes and flavonoids too.